Molecular biology of colon cancer (review)
Shaw, P.; Costa, J.
Anticancer Research 9(1): 21-27
1989
ISSN/ISBN: 0250-7005 PMID: 2539773 Document Number: 326506
In recent years molecular biology has been applied to the study of colonic carcinoma, both in the human and in the experimental animal. The data obtained have enriched our understanding of colonic carcinogenesis and are of potential interest for cancer diagnosis and prevention. In this paper we review part of the available literature on the molecular characterisation of colon tumors, with emphasis on the issues of clonality, in vitro cell lines, tumor progression and heredity of colon cancer.