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Study of biological equilibrium in the body in viral infection of different degree of severity (on the model of influenza)

Poliak, R.I.; Voĭtsekhovskiĭ, B.L.; Dubrovina, T.I.; Dukhin, A.I.; Ivanova, I.A.; Koltyreva, T.V.; Kramskaia, T.A.; Leont'eva, G.F.; Meringova, L.F.; Chetverikova, L.K.

Vestnik Akademii Meditsinskikh Nauk SSSR 4: 34-40

1991

ISSN/ISBN: 0002-3027
PMID: 1866985
Document Number: 374505
The authors made a comparative analysis of the contribution to the outcome of the disease by realization of information of viral genome and host responses in the time-course of simulated lethal and nonlethal mice influenza. They studied the effect of ionol, pathogenetic antioxidant, prevention and depicted absolutely new features of the diseases severity and outlined possible points of effective drug application. The suggested scheme of the time-course measurement of viral involvement of the host body and the formation of its responses could be recommended in the study of mechanisms of the viral infection development and the activity of antiviral agents.

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