Quantitative histochemical study of glucose-6-phosphatase in periportal and perivenous human hepatocytes
Chamlian, A.; Benkoel, L.; Bongrand, P.; Gulian, J.M.; Brisse, J.
Cellular and Molecular Biology 37(2): 183-190
1991
ISSN/ISBN: 0145-5680 PMID: 1652360 Document Number: 374283
The glucose-6-phosphatase activity of periportal and perivenous human hepatocytes was studied with a quantitative method. The results obtained with histogram of light intensity distributions indicate that the enzyme reaction was 1.3 to 2.5 fold higher in periportal zone than in perivenous zone. The profiles of light intensity along portal----hepatic venous distances show a progressive decrease of enzyme activity with highest values in periportal hepatocytes.