Clinical evaluation of cefotiam and cefamandole in respiratory tract infections
Beumer, H.M.; Olislagers, W.P.; Kahn, M.; van Hamersveld, J.D.
International Journal of Clinical Pharmacology Therapy and Toxicology 23(2): 105-108
1985
ISSN/ISBN: 0174-4879 PMID: 3886564 Document Number: 374
Eighty-two adult hospitalized patients suffering from respiratory tract infections were treated with cefotiam or cefamandole in an open comparative study. The patients were allocated randomly to 1 of 2 treatments. The recommended dosage regimens (i.m. or i.v.) were used for both groups (cefotiam 1 g twice a day, cefamandole 1 g three times a day). The duration of treatment was 7-14 days according to the response of the disease condition. Eighty patients were analyzed. The tolerability of both drugs was good and comparable. The clinical and bacteriological efficacy of both drugs was equivalent. The radiological examinations showed a better improvement of the patients treated with cefotiam.
Document emailed within 1 workday
