Coronary vascular reserve in heart transplantation. Normalization after therapy for rejection

Nitenberg, A.; Tavolaro, O.; Benvenuti, C.; Loisance, D.; Foult, J.M.; Hittinger, L.; Castaigne, A.; Cachera, J.P.; Vernant, P.; Nitenberg, A; Tavolaro, O; Benvenuti, C; Loisance, D; Foult, J.M; Hittinger, L; Castaigne, A; Cachera, J.P; Vernant, P

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Coronary vascular reserve in heart transplantation. Normalization after therapy for rejection

Nitenberg, A.; Tavolaro, O.; Benvenuti, C.; Loisance, D.; Foult, J.M.; Hittinger, L.; Castaigne, A.; Cachera, J.P.; Vernant, P.

Presse Medicale 20(40): 2053-2054

1991

ISSN/ISBN: 0755-4982

PMID: 1837126

Document Number: 373761

Acute rejection is associated with severe impairment of coronary reserve in heart transplants. To evaluate the effects of rejection therapy, coronary reserve was assessed in 6 patients before and after treatment of an acute episode of rejection. Coronary reserve was significantly enhanced after rejection therapy (4.7 +/- 0.8, vs 2.3 +/- 0.5, P less than 0.001) and was not significantly different from that of transplanted patients without rejection (5.4 +/- 0.8). This study provides evidence that alterations of coronary reserve due to acute rejection are reversible after treatment of the rejection episode.