Propranolol effect on GABA synthesis rate estimated by two different methods

Jastrzebski, Z.; Remiszewska, M.; Czyzewska-Szafran, H.; Wutkiewicz, M.

Acta Poloniae Pharmaceutica 48(1-2): 83-84

1991


ISSN/ISBN: 0001-6837
PMID: 1669424
Document Number: 372684
The propranolol effect on GABA synthesis rate in some brain structures using two different method was assessed. Both methods gave comparable results. Evaluation of the synthesis rate in vivo after inhibition of GABA degradation supplied more adequate information indicating that the availability of GABA precursor in the hypothalamus and the hippocampus is limited.

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