The concentrations of somatotropic hormone and insulin in the blood of heart surgery patients with a complicated course of the postoperative period
Kuznetsova, B.A.; Saprygin, D.B.; Kuliev, E.A.; Mikhaĭlova, I.L.; Poplavskaia, L.M.
Anesteziologiia i Reanimatologiia 3: 49-53
1991
ISSN/ISBN: 0201-7563 PMID: 1897796 Document Number: 372456
It has been shown that the course of the early postoperative period in cardiosurgical patients and its outcome is to a great extent related to adequate balance of adaptation hormones, whose levels and changes are determined by the functional state of compensatory-adaptive systems. Patients with favourable outcome of the complicated postoperative period along with synchronous activation of sympathoadrenal system (SAS), hypophyseoadrenal system (HAS) and an elevated somatotropic hormone (STH) level demonstrated adequately high blood insulin content, with the equilibrium in adrenalin/insulin and cortisol/insulin ratios retained, and moderate STH predominance over insulin. In 1/4 of patients with complicated postoperative period and unfavourable outcome an attenuated SAS response was accompanied by excessively high STH, ACTH, cortisol blood content and a lower insulin level, which determined relative insulin insufficiency.