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The course of the early postoperative period in heart surgery patients in relation to the state of humoral regulatory mechanisms

Kuznetsova, B.A.; Saprygin, D.B.; Kuliev, E.A.; Poplavskaia, L.M.; Mikhaĭlova, I.L.

Anesteziologiia i Reanimatologiia 5: 41-45

1989

ISSN/ISBN: 0201-7563
PMID: 2596716
Document Number: 346470
It has been shown that the course and outcome of the early postoperative period in cardiosurgical patients are to a great extent related to the functioning of the adaptation systems under study and their interrelations. An essential role of sympathoadrenal system (SAS) in the control over hormonal body status has been established. It ensures, provided its activity is retained, interaction of other hormonal systems as a uniform functional mechanism in postoperative stress. Decreased activity and intrasystemic coordination of SAS combined with low activity of renin-angiotensin-aldosterone system and excessively activated hypophyseal-adrenal system in patients with postoperative complications are indicative of adaptation mechanism damage and are of negative prognostic value.

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