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Coagulative activity and acid resistance of damaged and intact erythrocytes in various types of intravascular blood coagulation

Grigir'ev, G.P.; Usynin, V.V.

Gematologiia i Transfuziologiia 36(4): 13-15

1991

ISSN/ISBN: 0234-5730
PMID: 2065959
Document Number: 372357
Blood assay in patients with DIC-syndrome and thrombosis has shown different changes in red blood cell acid resistance: it is increased in acute noninfectious DIC-syndrome, and significantly decreased in the presence of sepsis, in patients with chronic DIC-syndrome and acute thrombophlebitis it is less lowered, while it is significantly elevated in the development of thromboembolism of the pulmonary artery. At the same time red blood cells damaged due to DIC-syndrome are characterized by increased acid resistance and high coagulation potential. This combination has proved the pathogenetic role of damaged red blood cells and the process of fragmentation in the development of intravascular blood coagulation.

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