Use of alpha interferon preparations in acute lymphoblastic leukemia in children during remission

Gavrilova, I.E.; Kuznetsov, I.P.; Denisov, L.A.; Maiakova, S.A.; Orlova, T.G.; Kadagidze, Z.G.; Makhonova, L.A.; Gavrilova, I.E; Kuznetsov, I.P; Denisov, L.A; Maiakova, S.A; Orlova, T.G; Kadagidze, Z.G; Makhonova, L.A

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Use of alpha interferon preparations in acute lymphoblastic leukemia in children during remission

Gavrilova, I.E.; Kuznetsov, I.P.; Denisov, L.A.; Maiakova, S.A.; Orlova, T.G.; Kadagidze, Z.G.; Makhonova, L.A.

Pediatriia 11: 75-78

1991

ISSN/ISBN: 0031-403X

PMID: 1766748

Document Number: 371741

The Soviet alpha-interferon drugs (human leukocytic interferon, reaferon) were used in the program of the treatment of children with acute lymphoblastic leukemia (during remission). The treatment was found to be more effective with an increase of its duration, relapse-free course of the disease (69.4-82.3%) and survival (70.1-93.1%) of patients with an unfavourable disease prognosis (over 5 years).