Effects of low-dose oral contraceptives on sugar metabolism
Miccoli, R.; Orlandi, M.C.; Fruzzetti, F.; Melis, G.B.; Giampietro, O.; Ricci, C.; Bertolotto, A.; Masoni, A.; Penno, G.; Fioretti, P.
Minerva Ginecologica 41(9): 441-444
1989
ISSN/ISBN: 0026-4784 PMID: 2695866 Document Number: 369697
The effects on carbohydrate metabolism by four low-dose oral contraceptives were evaluated in four low-dose oral contraceptives were evaluated-66 young women randomly divided in four groups. In the various preparations there were a different dosage of estrogen (ethinylestradiol) together different doses and types of progestogen (desogestrel, gestodene, cyproterone acetate). After six months of treatment, in all groups a slight increase of glycemic and insulinemic responses during OGTT was observed; the significance was achieved with the preparation containing cyproterone acetate alone. Glycated hemoglobin did not change. Our results suggest that these new low-dose oral contraceptives induced negligible metabolic side effects.