Importance of levonorgestrel dose in oral contraceptives for effects on coagulation

Kluft, C.; de Maat, M.P.; Heinemann, L.A.; Spannagl, M.; Schramm, W.

Lancet 354(9181): 832-833

1999


ISSN/ISBN: 0140-6736
PMID: 10485729
DOI: 10.1016/s0140-6736(99)80017-8
Document Number: 523483
Combined oral contraceptives show clear differences in effect on the tissue factor-initiated coagulation test of activated protein C resistance, which is dependent on the presence and dosage of levonorgestrel. Multiphasic levonorgestrol oral contraceptives differ from monophasic contraceptives and resemble third-generation contraceptives.

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