A double-blind comparison of the new ibuprofen-codeine phosphate combination, zomepirac, and placebo in the relief of postepisiotomy pain
Cater, M.; O'Brien, P.M.; Pickvance, N.J.
Clinical Therapeutics 7(4): 442-447
1985
ISSN/ISBN: 0149-2918 PMID: 3893701 Document Number: 3694
In a double-blind, single-dose study, the analgesic effect of a combined ibuprofen-codeine phosphate preparation was compared with those of zomepirac and placebo in 127 patients with moderate or severe postepisiotomy pain. Both the combination and zomepirac were significantly more effective than placebo for up to six hours, but the onset of action of the combination was more rapid than that of zomepirac. The study was notable for the virtual absence of side effects.
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