Modulation of humoral immune responses by Tinospora malabarica in experimental animals
Bhattacharya, S.K.; Maity, P.C.; Mediratta, P.; Sen, P.
Indian Journal of Experimental Biology 29(10): 971-972
1991
ISSN/ISBN: 0019-5189 PMID: 1726092 Document Number: 369346
Effect of alkaloidal fraction of aqueous extract of T. malabarica (Tm) was studied on humoral antibody responses in rats and guineapigs. The anti-SRBC haemagglutination titre was found to be enhanced in rats pretreated with Tm (2.5 mg/kg). Passive cutaneous anaphylaxis (PCA) in rats was also increased in Tm treated group. In vitro experiments with sensitized rat peritoneal mast cells showed a significant decrease in antigen-induced various spasmogens on isolated guineapig ileum.