Candida antibodies in amniotic fluid
Mathai, M.; Mathai, E.; Jairaj, P.
Indian Journal of Medical Research 93: 353-355
1991
ISSN/ISBN: 0019-5340 PMID: 1797642 Document Number: 369309
Amniotic fluid samples were tested for specific immunoglobulins against Candida albicans by indirect immunofluorescence. Nineteen of the 23 samples tested contained specific IgA while specific IgG antibodies were detected in only seven samples (P less than 0.01). None of the samples contained specific anticandidal IgM (P less than 0.001). These 23 samples and a further 30 amniotic fluid samples were tested for Candida mannan antigen by latex agglutination. Mannan was not detected in any of the samples tested. It is concluded that anticandidal IgA in amniotic fluid is naturally occurring.