Sodium chloride-induced hypergastrinaemia in rats
Awad, H.A.
Journal of the Egyptian Public Health Association 66(1-2): 73-77
1991
ISSN/ISBN: 0013-2446 PMID: 1800626 Document Number: 368425
In this study the effect of Nac1 on plasma immunoreactive gastrin was investigated. I.P. administration of sodium chloride (0.9%) in a dose of 1 ml/kg.b.w. for 7 days in rats, produced a significant rise in level of sodium ion in plasma. This hypernatraemia was also accompanied by significant rise in values of plasma immunoreactive gastrin. The mechanism(s) of this sodium chloride-induced release of gastrin is discussed.
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