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Determination of neuropeptide y concentration in the cerebrospinal fluid in patients with cerebrovascular diseases and its significance

Cao, X.H.; Kang, D.X.; Yang, L.H.

Zhonghua Nei Ke Za Zhi 30(7): 429

1991

ISSN/ISBN: 0578-1426
PMID: 1752158
Document Number: 368086
Concentration of neuropeptide Y (NPY) in the cerebrospinal fluid (CSF) of patients with cerebrovascular diseases was measured by using radioimmunoassay. The results showed that NPY concentration in CSF in patients with hemorrhagic cerebrovascular diseases (HCVD) was 4148 +/- 397.2 pg/ml, being significantly higher than the control level of 1083.7 +/- 245.8 pg/ml. While the NPY concentration in CSF of patients with ischemic cerebrovascular diseases (ICVD) was 2214 +/- 289.2 pg/ml, being not significantly different from the level in the control group. The effect of NPY in vasospasm after HCVD was preliminarily discussed.

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