Aggregation of denatured membrane proteins--the initial stage of acid hemolysis

Ivanov, I.T.; Benov, L.T.

Biofizika 36(5): 839-844

1991


ISSN/ISBN: 0006-3029
PMID: 1799598
Document Number: 367809
Influence of some sulfhydryl reagents on kinetics of acid hemolysis has been investigated. The results obtained indicate that the mechanism of acid hemolysis includes aggregation of some denatured membrane integral proteins, following the intermolecular disulfide bond formation. A suggestion is made that in this hemolysis-inducing aggregation free SH-groups containing proteins only take place.

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