The effect of contraceptive suppository of morrhuatic acid on lactobacilli in the vagina
Wu, J.Y.; Jin, Y.C.
Sheng Zhi Yu Bi Yun 10(1): 38-42
1990
ISSN/ISBN: 0253-357X PMID: 12316200 Document Number: 367663
The positive incidence of vaginal lactobacilli after culture was 69.7% in 33 volunteers tested by the quantitative method. Those positive patients were divided into different groups for study. 21 used morrhuatic acid and become group 1. Their log10 X+or- Se of lactobacilli was 7.9545 +or- 0.2748 before the suppository was used, 8.3422 +or- 0.1910/12 hours after suppository use, and the paired t value was 2.4327. The geometric mean of lactobacilli was significantly higher at 12 hours after treatment (p0.05). The 2nd group of 17 subjects who were sexually active had levels of quantitative lactobacilli of 7.7435 +or- 0.2968/12 hours after sexual activity, and no statistical significance were found although that was lower than 8.0587 +or- 0.2129 prior to sexual activity. The 6 subjects who were sexually active and who were tested both before and after the use of morrhuatic acid served as the 3rd group. There the levels of lactobacilli before and after treatment (with sexual activity) were quite close, 8.2475 +or- 0.0891 and 8.0219 +or- 0.2840, respectively. Results revealed that the vaginal lactobacilli were not affected by the morrhuatic acid suppository. (author's modified)