Molecular-biochemical mechanisms of the effects of nootropic agents
Kresiun, V.I.; Rozhkovskiĭ, I.V.
Biulleten' Eksperimental'noi Biologii i Meditsiny 110(7): 58-60
1990
ISSN/ISBN: 0365-9615 PMID: 2224104 Document Number: 367227
It is a known fact that prophylactic hypodermic injection of non-typical lithonite tranquillizer in the day's dose of 30 mg/kg during 10 days prevents the exhaustion of antioxidant system of the body, normalizes qualitative and quantitative correlation of separate fractions of phospholipids, stabilizes the permeability of erythrocytic membranes and prevents the development of hypercholesterolemia of the stress. It is concluded that the lithonite's stress-protecting effect is the result of its membrane stabilizing influence.