Use of monoclonal antibodies for studying cytochrome P-450 forms. use of interspecies homology of amino acid sequence

Brauze, D.; Pawlak, A.L.

Folia Medica Cracoviensia 31(3): 121-130

1990


ISSN/ISBN: 0015-5616
PMID: 2097277
Document Number: 365787
The current research on utilization of monoclonal antibodies for isolation of cytochrome P-450 forms, substrate specificity determination, localization in tissues and contribution in DNA adduct formation is reviewed in this paper. Usefulness of monoclonal antibodies directed against rodent cytochrome P-450 isoenzymes to human investigations is emphasized.

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