Solid facial edema associated with acne. Therapeutic efficacy of isotretinoin
Humbert, P.; Delaporte, E.; Drobacheff, C.; Piette, F.; Blanc, D.; Bergoend, H.; Agache, P.
Annales de Dermatologie et de Venereologie 117(8): 527-532
1990
ISSN/ISBN: 0151-9638 PMID: 2146915 Document Number: 365324
Persistent solid facial edema is considered a complication of acne vulgaris and has never been reported in the French literature. The authors report the cases of 2 patients, a 15-year old girl and a 20-year old man, who suffered from the condition for 1 and 2 years respectively. Clinical features and course are described. Treatment with isotretinoin in doses of 1 mg/kg/day administered during 6 and 8 months resulted in an 80 p. 100 and 50 p. 100 reduction of the edema respectively.