Inflammatory acne resistant to conventional therapy. Efficacy and tolerability of isotretinoin
Scaglione, R.; Desirello, G.; Pazzaglia, A.
Giornale Italiano di Dermatologia e Venereologia Organo Ufficiale Societa Italiana di Dermatologia e Sifilografia 124(3): Xiii-Xxix
1989
ISSN/ISBN: 0392-0488 PMID: 2530160 Document Number: 345389
The effectiveness and tolerance of isotretinoin have been assessed in 72 cases (34 male and 38 female) suffering from papulo-pustular acne with nodulo-cystic component recalcitrant to traditional treatments. The drug confirmed its noteworthy effectiveness and speed of action in all cases. Stress is laid in particular on the lack of recurrence even after a very long-term follow-up. Tolerance was also very good with a prevalent incidence of mucocutaneous signs (desquamation, cheilitis, dermatitis) and the consequent acceptability of treatment on the part of patients.