Gonadal dysgenesis
Lisá, L.; Horejsí, J.; Goetz, P.; Zuntová, A.; Dvorák, P.
Ceskoslovenska Pediatrie 45(9): 520-522
1990
ISSN/ISBN: 0069-2328 PMID: 2078886 Document Number: 362850
The authors describe six patients, female phenotype with karyotype 45X/46XY. Two girls suffered from pure gonadal dysgenesis, four from mixed gonadal dysgenesis. The authors emphasize the intact axis hypothalamus-pituitary gonads. In the above diagnoses the authors recommend revision and extirpation of the gonads with regard to possible malignant growth in the dysgenetic gonad.