A decrease in the activity of the nucleolar organizers of the gastric and duodenal mucosal cells in peptic ulcer patients
Sorin, V.F.; Morozov, V.P.; Mamaev, N.N.; Kudrevatykh, I.P.; Shchetinin, V.N.
Terapevticheskii Arkhiv 62(2): 33-35
1990
ISSN/ISBN: 0040-3660 PMID: 1692425 Document Number: 362424
Silver plating of nucleoli was used to study the activity of nucleolar organizers (NO) in the cells of one-layer prismatic epithelium of the gastric and duodenal mucosae. The activity of NO was established to be lowered in patients suffering from ulcer disease and in patients with compression stenosis of the celiac trunk, which may point to the impairment of protein synthetic processes in the cells. Factor of ischemia as the most probable cause of the enumerated changes is under discussion.