Distribution of neutralizing antibodies to California and Bunyamwera serogroup viruses in horses and rodents in California
Campbell, G.L.; Reeves, W.C.; Hardy, J.L.; Eldridge, B.F.
American Journal of Tropical Medicine and Hygiene 42(3): 282-290
1990
ISSN/ISBN: 0002-9637 PMID: 2107770 Document Number: 361849
Neutralization tests were done on sera (collected in 1968 or 1971-72) from 141 horses from high elevation regions of California. Antibody prevalences to Jamestown Canyon, snowshoe hare and California encephalitis viruses in the California serogroup and Northway virus in the Bunyamwera serogroup were 55, 43, 18 and 46%, respectively. In 51 horses from rural low elevation regions, seroprevalences were 31, 35, 35 and 37%, respectively. Twenty-four horses from suburban lowland area were seronegative, except for a single horse with a low titre to snowshoe hare virus. Seroprevalence to Jamestown Canyon and snowshoe hare viruses was associated with increasing age. Only 2 of 177 rodents (1/83 Spermophilus lateralis and 1/55 Eutamias amoenus) from the Sierra Nevada had antibodies to Northway virus (sera collected in 1987); none had antibodies to Jamestown Canyon or snowshoe hare viruses. Neutralization tests were done on sera from 141 horses from high elevation regions of California. Antibody prevalences to Jamestown Canyon, snowshoe hare, and California encephalitis viruses in the California serogroup and Northway virus in the Bunyamwera serogroup were 55%, 43%, 18%, and 46%, respectively. In 51 horses from rural low elevation regions, seroprevalences were 31%, 35%, 35%, and 37%, respectively. Twenty-four horses from a suburban lowland area were seronegative, except for a single horse with a low titer to snowshoe hare virus. Seroprevalence to Jamestown Canyon and snowshoe hare viruses was associated with increasing age. Only 2 of 177 rodents from the Sierra Nevada had antibodies to Northway virus; none had antibodies to Jamestown Canyon or snowshoe hare viruses. [Serum from the horses was collected in 1968 and 1971-72 and from the rodents in 1987.]AS.