A progressive gastric cancer in which preoperative oral chemotherapy resulted in a histopathological "Grade 2" rating
Hiromoto, M.; Yasui, A.; Nishida, Y.; Kumagai, K.; Sanada, Y.; Masuo, K.; Kobayashi, K.; Nakayama, A.
Gan no Rinsho. Japan Journal of Cancer Clinics 36(6): 747-751
1990
ISSN/ISBN: 0021-4949 PMID: 2140866 Document Number: 361426
This paper describes a case of a Borrmann type 3 gastric cancer, in which the preoperative intermittent oral administration of 5'-DFUR over a short term resulted in a histopathological rating of Grade 2. A 56-year-old man preoperatively received an intermittent, oral administration of 5'-DFUR, 2, 100 mg/day. An upper gastrointestinal series and endoscopy revealed macroscopically an extremely slight remission. Histopathologically, however, a widespread, remarkable degeneration of cancer cells and fibrinogenesis of the framework were observed, these results leading to a change of rating to Grade 2.