The in vitro sensitivity of Bacteroides gingivalis and Bacteroides intermedius to different classes of antibiotic chemical molecules
Paolantonio, M.; Bascelli, A.; Tetè, S.; Scaramella, F.; Piccolomini, R.
Minerva Stomatologica 39(5): 347-352
1990
ISSN/ISBN: 0026-4970 PMID: 2381396 Document Number: 361256
A study was carried out to assess the in vitro sensitivity of Bacteroides gingivalis and Bacteroides intermedius to various classes of chemio-antibiotic molecules. The activities of two cephalosporins (cefuroxime and cefotaxime), which have never previously been used for periodontal therapy, were also evaluated. Results showed that the cephalosporins possessed an equal or greater inhibitory activity against the bacteria studied than traditional tetracyclines, and a greater inhibitory activity than other antibiotics studied (metronidazole, ampicillin, piperacillin). Further studies are required to assess in vivo efficacy of cephalosporin therapy in severe periodontal diseases.