The mechanism of acquired immunity in experimental giardiasis
Romia, S.A.; Abou-Zakham, A.A.; Hegazi, M.M.
Journal of the Egyptian Society of Parasitology 20(2): 607-614
1990
ISSN/ISBN: 1110-0583 PMID: 2230316 Document Number: 361223
Giardia-spontaneously cured mice were rendered resistant to challenge infection. This was documented by the decreased cyst excretion rate comparable to the control ones. Endoxan and irradiation treatment caused a breakdown in both humoral and cellular immunity. Immune-depressed mice were more susceptible to Giardia infection, thus proving the active role of antibodies and cell-mediated immune response in giardiasis.