Diagnosis of Campylobacter pylori based on the level of urea in the gastric juice
Rozhavin, M.A.; Sologub, V.V.; Mikitiuk, I.I.; Popereka, G.M.; Iurchenko, E.S.; Perederiĭ, V.G.
Laboratornoe Delo 4: 6-9
1990
ISSN/ISBN: 0023-6748 PMID: 1695282 Document Number: 360516
Comparison of urea levels in 3 portions of gastric juice, obtained on an empty stomach, basal, and stimulated, from 28 patients, C. pylori carriers, and 20 patients without C. pylori carriership, has shown that the presence of this bacterium in the gastric mucosa is related not so much with a decrease in the absolute level of urea in the portion collected on an empty stomach but mostly with changes in this parameter in three portions of gastric juice collected in succession. Decreased urea levels in the second portion as against the first one or in the third one as against the two previous ones were detected in 97% of patients with C. pylori carriership. In 100% of patients without C. pylori carriership urea levels in the three portions remained unchanged or were decreasing. The method for measuring urea levels in three portions of gastric juice is recommended for the diagnosis of C. pylori carriership in gastroduodenal diseases.