Mineralization of polyurethane membranes in the total artificial heart (TAH) : a retrospective study from long-term animal experiments

Dostál, M.; Vasků, J.; Vasků, J.; Sotolová, O.; Vasků, A.; Dolezel, S.; Hartmannová, B.

International Journal of Artificial Organs 13(8): 498-502

1990


ISSN/ISBN: 0391-3988
PMID: 2228292
Document Number: 360483
The degree of mineralization of TAH membranes in animals is directly related to the survival time of animals with a TAH. Large differences in mineralization of the membranes among individual animals have been observed. These differences can be explained by the simultaneous presence of infection on biomaterials (polyurethane) as well as by different levels of natural inhibitors of mineralization. No positive influence of applying sodium warfarin for the inhibition of the mineralization was observed.

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