Kyrle disease--a case report
Sorhage, B.; Glowania, H.J.; Schäfer, R.
Zeitschrift für Hautkrankheiten 65(9): 847-850
1990
ISSN/ISBN: 0301-0481 PMID: 2264378 Document Number: 359901
Based on a case of our own observation, we present the characteristic features of a rare skin disease: hyperkeratosis follicularis et parafollicularis in cutem penetrans, i.e. Kyrle's disease. The clinical picture shows follicular and interfollicular hyperkeratotic horn-like plugs with a typical distribution pattern. The classical histological features are epidermolysis and hyperkeratoses advancing towards the dermis. Today, this disease is regarded as a genodermatosis with recessive heredity and is best treated with systemic and topical application, resp., of vitamin A acid.