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The use of the macrophage disappearance reaction for detecting delayed hypersensitivity to Yersinia pestis antigens

Vasil'eva, G.I.; Doroshenko, E.P.; Kiseleva, A.K.; Pustovalov, V.L.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 12: 83-86

1990

ISSN/ISBN: 0372-9311
PMID: 2099076
Document Number: 358773
The possibility of using the reaction of macrophage disappearance (RMD) for the detection of delayed hypersensitivity (DH) to Y. pestis has been studied. As the result of these studies, RMD has been found suitable, in principle, for use in the quantitative evaluation of DH to Y. pestis. High sensitivity and specificity of this reaction have been established. The presence of DH in the process of the formation of immunity after immunization with Y. pestis antigen FIA has been shown. RMD can be observed during 28 days after immunization (the term of observation).

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