Selective photoreceptor cell loss in hypoxic ischemia
Holman, R.E.; Peiffer, R.L.; Bouldin, T.W.; Grimson, B.S.
Annals of Ophthalmology 22(9): 335-338
1990
ISSN/ISBN: 0003-4886 PMID: 2248490 Document Number: 358697
We studied the histopathologic changes in the brain and eye of a 5 1/2-month-old infant who suffered a profound hypotensive episode three days antemortem. Nuclear pyknosis and other histologic changes characteristic of ischemic cell necrosis were found throughout the brain and in the retina's photoreceptor-cell layer. These findings suggest that hypoxic ischemia may produce preferential damage to the photoreceptor-cell layer.
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