Membrane-associated protease activity of human erythrocytes

Naik, A.A.; Chakrabarti, S.

Indian Journal of Medical Research 92: 378-382

1990


ISSN/ISBN: 0019-5340
PMID: 2272677
Document Number: 358611
Membrane-associated protease activity capable of digesting a number of membrane cytoskeletal proteins including band 3 protein was identified in human erythrocytes, almost totally free from contaminating leucocytes and platelets. This enzyme was inhibited by aprotinin (a specific inhibitor for a class of serine protease) and was distinct from the cytosolic calcium-dependent thiol protease (calpain), which is also known to bind to red cell membrane.

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