Effect of partial pressure of solute oxygen on the intensity of respiration of cultures of antibiotic producers
Arzumanian, O.G.; Shnaĭder, L.E.; Tarasova, S.S.; Biriukov, V.V.; Mal'tsev, N.I.
Antibiotiki i Khimioterapiia 35(1): 14-19
1990
ISSN/ISBN: 0235-2990 PMID: 2334239 Document Number: 358496
It was shown possible to use feeding of hydrogen peroxide as a method for investigating the impact of dissolved oxygen concentrations on growth and development of microorganisms. The influence of pO2 on the respiration intensity was studied in penicillin- and erythromycin-producing cultures and it was found that dependence of the respiration intensity on pO2 had the form of a curve with saturation, at pO2 equal to zero the value of the culture respiration intensity being different from zero. A mathematical model accounting for the presence in the fermentation broth of microbial agglomerates with the average size depending on the agitation conditions is proposed for describing the relationships.