Alpha-1-proteinase inhibitor gene frequencies in Belgium
Kimpen, J.; Legius, E.; Bosmans, E.; Van Vaerenbergh, V.; Ramon, A.; Raus, J.
Gene Geography a Computerized Bulletin on Human Gene Frequencies 4(3): 159-163
1990
ISSN/ISBN: 0394-249X PMID: 2129618 Document Number: 358439
The alpha-1-antitrypsin phenotype was determined in cord blood of 1345 Belgian newborns by isoelectric focusing in polyacrylamide gels. Proteinase inhibitor (PI) gene frequencies were calculated. The relative gene frequency of the M allele was 0.9245, and those of S and Z alleles were 0.0543 and 0.0167 respectively. I and F alleles were less represented. These results are in agreement with population studies of neighbouring countries.
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