Preventive effect of aluminium citrate on silicosis
Zou, S.Q.; Liu, H.; Zhou, Y.Y.; Su, K.Q.; Qi, K.Y.; Guan, S.M.; Liu, S.J.
Chinese Medical Journal 103(2): 173-176
1990
ISSN/ISBN: 0366-6999 PMID: 2167820 Document Number: 358383
Aluminium citrate (Al-cit) was shown to be biologically effective in preventing silicosis. A total of 917 cases selected from both engineering corps of railway and coalmines with stage 0 or 0+ by radiographs were studied. Cases were randomly divided into Al-cit treatment group and control group with continuing dust exposures. Workers in the treatment group were injected with Al-cit at a dose of 120 mg Al/year and those in the control group received a consolatant or nothing during the period of five years. The radiographic changes demonstrated that Al-cit showed clear-cut effects in both retardation of the dust-induced fibrosis and decrease of the morbidity of silicosis.