Immunophenotype of lymphocytic infiltrate in mycosis fungoides at the plaque stage and at the tumor stage. a comparative study
Cerroni, L.; Peris, K.; Torlone, G.; Chimenti, S.
Giornale Italiano di Dermatologia e Venereologia Organo Ufficiale Societa Italiana di Dermatologia e Sifilografia 125(7-8): 313-317
1990
ISSN/ISBN: 0392-0488 PMID: 2289812 Document Number: 358191
An immunohistochemical study of 18 cases of mycosis fungoides (8 cases in tumor stage, 10 in plaque stage) is reported. Seven immunohistochemical parameters were set to evaluate the immunophenotype of the lymphocytes int he two stages of the disease. The results showed loss of differentiation and marked activation of the neoplastic lymphocytes with the progression of the disease from plaque to tumor stage.