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Metabolism of purine and pyrimidine compounds in erythrocytes of tumor-bearing mice

Tikhonov, Y.V.; Pimenov, A.M.; Toguzov, R.T.; Grune, T.; Siems, W.; Schmidt, H.; Gerber, G.

Biomedica Biochimica Acta 49(2-3): S125-S128

1990

ISSN/ISBN: 0232-766X
PMID: 2386497
Document Number: 357852
The pattern of purine and pyrimidine derivatives was studied in the erythrocytes of C3HA and ICR mice during Hepatoma 22 and Ehrlich ascites tumor cell growth. Concentrations of purine nucleotides, nucleosides and nucleobases of host erythrocytes were changed after the implantation of the tumors. The host erythrocytes markedly concentrated adenine and guanine nucleotides both during logarithmic and plateau phase of tumor growth (5th and 11-12th days after inoculation of the tumor). The contents of nucleosides and nucleobases in the red blood cells were decreased during the logarithmic growth phase but restored within the plateau phase.

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Tikhonov, I.V.; Meĭsner, I.S.; Pimenov, A.M.; Toguzov, R.T. 1989: Features of purine compound metabolism in hepatoma 22, mouse liver and erythrocytes during tumor development Voprosy Meditsinskoi Khimii 35(3): 125-129
Kotsiuruba, A.V.; Akhmed, I.; Tarakanov, S.S.; Kholodova, I.D. 1992: Effect of ecdysterone on the metabolism of purine and pyrimidine nucleotides in chicken tissues Ukrainskii Biokhimicheskii Zhurnal 64(5): 52-60
Wolski, T. 1978: The choice of medium suitable for the reaction of thiol groups with halogen derivatives in the synthesis of some purine and pyrimidine compounds. I. Synthesis of azathioprine Polish Journal of Pharmacology and Pharmacy 30(4): 593-599
Tanaka, K.; Koga, Y.; Taniguchi, K.; Nomoto, K. 1987: T-cell recruitment from the thymus to the spleen in tumor bearing mice: phenotypical alteration and recruitment of thymocytes raised in a tumor bearing state Cancer Research 47(8): 2136-2141
Gurevish, S.M.; Vartanian, L.S.; Nagler, L.G. 1993: Disorders in metabolism of superoxide radicals in tumor-bearing mice during development of Ehrlich ascites carcinoma and their normalization under the effect of ruboxyl Voprosy Meditsinskoi Khimii 39(6): 16-20
Fisher, B.; Saffer, E.A. 1978: Tumor cells cytotoxicity by granulocytes from peripheral blood of tumor-bearing mice Journal of the National Cancer Institute 60(3): 687-691
Iunker, V.M.; Arkhipov, S.A.; Gruntenko, E.V. 1984: Ambiguous action of splenocytes from tumor-bearing mice on the formation of metastases in the lungs of mice in an adaptive transfer system Biulleten' Eksperimental'noi Biologii i Meditsiny 98(11): 598-600
Zardi, L.; Cecconi, C.; Barbieri, O.; Carnemolla, B.; Picca, M.; Santi, L. 1979: Concentration of fibronectin in plasma of tumor-bearing mice and synthesis by Ehrlich ascites tumor cells Cancer Research 39(9): 3774-3779
Ikenaka, K.; Fukushima, M.; Nakamura, H.; Okamoto, M.; Shirasaka, T.; Fujii, S. 1981: Metabolism of pyrimidine nucleotides in various tissues and tumor cells from rodents Gan 72(4): 590-597
Tamura, K.; Ishida, N. 1984: Induction of tumor necrosis factor (TNF) in tumor-bearing mice Gan to Kagaku Ryoho. Cancer and ChemoTherapy 11(7): 1369-1378
Fine, D.L.; Arthur, L.O.; Gardner, M.B. 1978: Prevalence of murine mammary tumor virus antibody and antigens in normal and tumor-bearing feral mice Journal of the National Cancer Institute 61(2): 485-491
Shi, L.; Chen, J.; Zhong, Q.; Geng, P.; He, J. 2014: Anti-tumor effect of Sendai virus Tianjin strain defective interfering particles on tumor-bearing mice Zhonghua Zhong Liu Za Zhi 36(3): 177-182
Aicher, K.P.; Dupon, J.W.; White, D.L.; Aukerman, S.L.; Moseley, M.E.; Juster, R.; Rosenau, W.; Winkelhake, J.L.; Brasch, R.C. 1990: Contrast-enhanced magnetic resonance imaging of tumor-bearing mice treated with human recombinant tumor necrosis factor alpha Cancer Research 50(22): 7376-7381
Fedorov, N.A.; Matveenko, V.N.; Tikhonova, E.F. 1970: Utilization of pyrimidine precursors in the tumor and liver of mice with Ehrlich ascites carcinoma Biulleten' Eksperimental'noi Biologii i Meditsiny 70(12): 66-69
Piskur, J.; Søndergaard, L.; Gojkovic, Z.; Stokbro, B.; Hjulsager, C.; Davidson, J.; DeMoll, E.; Rawls, J.; Bahn, E. 1994: Observed resistance to pyrimidine analogs and sensitivity to uracil in Drosophila is attributed to deregulation of pyrimidine metabolism Advances in Experimental Medicine and Biology 370: 559-565
Warren, P.; Song, W.; Holle, E.; Holmes, L.; Wei, Y.; Li, J.; Wagner, T.; Yu, X. 2002: Combined HSV-TK/GCV and secondary lymphoid tissue chemokine gene therapy inhibits tumor growth and elicits potent antitumor CTL response in tumor-bearing mice Anticancer Research 22(2a): 599-604
Tzai, T.S.; Shiau, A.L.; Liu, L.L.; Wu, C.L. 2000: Immunization with TGF-beta antisense oligonucleotide-modified autologous tumor vaccine enhances the antitumor immunity of MBT-2 tumor-bearing mice through upregulation of MHC class i and Fas expressions Anticancer Research 20(3a): 1557-1562
Oparin, D.A.; Gorenshteĭn, B.I.; Karaedova, L.M.; Naruta, E.E.; Zabrodskaia, S.V.; Rudiak, T.V.; Akat'ev, V.E.; Larin, F.S. 1997: Effect of hydroxylated pyrimidine derivatives on activities of thiamine-dependent enzymes and some parameters of lipid metabolism in mice Ukrainskii Biokhimicheskii Zhurnal 69(1): 37-41
Zou, J.P.; Shimizu, J.; Ikegame, K.; Yamamoto, N.; Ono, S.; Fujiwara, H.; Hamaoka, T. 1992: Tumor-bearing mice exhibit a progressive increase in tumor antigen-presenting cell function and a reciprocal decrease in tumor antigen-responsive CD4+ T cell activity Journal of Immunology 148(2): 648-655
Kamo, I.; Ishida, N. 1971: Immune response in tumor-bearing mice Gan 62(6): 453-458