Chemotherapeutic pathomorphosis of breast cancer
Frank, G.A.; Volchenko, N.N.; Borisov, V.I.
Sovetskaia Meditsina 11: 14-16
1990
ISSN/ISBN: 0038-5077 PMID: 1963707 Document Number: 357558
Features of pathomorphism of mammary carcinoma were studied in 177 women after a course of drug therapy. Qualitative and quantitative morphologic changes in the tumor were poorly manifest: they were detected in only 54 percent of patients and only in 9 percent the effect was manifest (third-fourth stage of involvement). Characteristic findings here were augmentation of cellular dystrophy, necrotic changes, enhanced nuclear polymorphism; significant injury to tumor parenchyma was paralleled by development of xanthomatosis foci and lymphoid histiocytic infiltration.
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