A toxicological hygiene study of a dye made from abattoir blood for sausage products
Lerina, I.V.; Belous, A.M.; Kolesnik, T.L.; Shatrov, G.N.; Kozlova, V.F.; Zaĭtsev, A.N.
Voprosy Pitaniia 1: 61-64
1990
ISSN/ISBN: 0042-8833 PMID: 2346015 Document Number: 357448
Toxicologic and hygienic study of a pigment from abattoir blood--carboxyn (based on carboxyhemoglobin) was conducted on noninbred white rats in subacute (3 months) and chronic (12 months) experiments. The condition of the animals, their bw growth, blood morphology, erythrocyte sedimentation rate, the content of hemoglobin, protein and iron in the blood serum were evaluated. Activity of the following enzymes was studied: catalase and sorbitol dehydrogenase--in the blood serum; glucose 6-phosphate dehydrogenase, lactate dehydrogenase and cytochrome P-450 content--in the liver. Internal organs of the rats were subjected to histological investigation. The data obtained have evidenced the absence of some signs of biotransformation of the red complex of carboxyhemoglobin, or its toxic effect on the experimental animals. It has been concluded that carboxyn can be used as a coloring component in the production of sausage (in the amount of up to 2% of the sausage meat mass).