The activity of several enzymes in the urine and blood of animals in experimental poisoning with sublimate. Part. II. Chronic poisoning
Starnawska, M.; Hać, E.
Bulletin of the Institute of Maritime and Tropical Medicine in Gdynia 41(1-4): 89-96
1990
ISSN/ISBN: 0324-8542 PMID: 1983769 Document Number: 355924
Fourteen guinea pigs were injected with sublimate during the period of 3 months. Their urine and blood was examined. In the urine an increase of activity of alkaline phosphatase and lactate dehydrogenase was noted. In the blood plasma an increase of lactate dehydrogenase activity was observed and in the blood serum decrease of gamma-glutamyl-transpeptidase activity. The determination of alkaline phosphatase in urine is a sensitive indicator of renal damage caused by mercury. It has a greater diagnostic value than the determination of this enzyme in the blood serum.