Pentamidine-induced cardiotoxicity
Glikson, M.; Dresner-Feigin, R.; Pollack, A.; Wolf, D.; Galun, E.; Tur-Kaspa, R.
Israel Journal of Medical Sciences 26(10): 588-589
1990
ISSN/ISBN: 0021-2180 PMID: 2249939 Document Number: 355535
The cases of a 29-year-old man who had undergone renal transplantation, and a 28-year-old HIV-positive male from Israel, with pentamidine-induced cardiotoxicity following treatment for Pneumocystis carinii pneumonia, are reported. Both patients had evidence of pentamidine-induced ECG changes; QT prolongation and T wave inversion appeared during treatment and resolved after the drug was discontinued.