The determination of free and bound oxyproline in urine
Sharaev, P.N.; Botnikova, E.A.; Ivanov, V.M.; Zubarev, O.N.; Malinin, O.V.; Zubkova, S.V.
Laboratornoe Delo 12: 23-25
1990
ISSN/ISBN: 0023-6748 PMID: 1710687 Document Number: 354152
A method of measuring urinary free, peptide- and protein-bound hydroxyproline is suggested. Adults were found to excrete 18 mumol of free, 155 mumol of peptide-bound, and 8 mumol of protein-bound hydroxyproline daily. In children daily urinary levels of free and peptide-bound hydroxyproline were higher. Data are presented on changes in various hydroxyproline forms in pneumonia, rheumatic fever, and hemorrhagic fever with the renal syndrome.