Male sterility and reciprocal translocation (4;15) . Description of a case
Piovani, G.; Zanelli, P.; Neri, T.M.; Savi, M.
Acta Bio-Medica de l'Ateneo Parmense 61(3-4): 149-153
1990
ISSN/ISBN: 0392-4203 PMID: 2151914 Document Number: 352847
Chromosome abnormalities in infertile males are not infrequent, ranging from 4% to about 1% for sex and autosomal chromosomes respectively. Autosomal abnormalities mainly consist of balanced translocations, mostly robertsonian. The Authors report a case of reciprocal translocation t (4;15) associated with oligozoospermia and sterility in a 37 years-old man. The break-points involved in the translocation (4q25; 15p11) seem to be quite uncommon. The possible relationship between this unusual translocation and sterility is discussed.