Defibrotide and heparin in the prevention of deep venous thromboses. A controlled study
Villani, L.G.; Dalla Valle, R.; Rubini, P.
Minerva Chirurgica 45(15-16): 1029-1033
1990
ISSN/ISBN: 0026-4733 PMID: 2280855 Document Number: 352476
Forty-one surgical patients at risk of deep venous thrombosis (DVT) were treated with defibrotide (400 mg/b.i.d./i.v.) or with heparin (5000 UI/t.i.d./s.c.). Neither DVT nor pulmonary embolism was evidenced. In the heparin group the healing rate was longer and during the first three days bleeding from the surgical wound was more pronounced. In particular one patient of the heparin group had to interrupt the treatment for haemorrhage.