Rapid diagnosis of streptococcal pharyngitis with enzyme immunoassay
Chu, J.M.; Chen, J.M.; Wu, M.H.; Hong, J.Y.; Wang, Y.M.; Hsu, H.H.; Lue, H.C.
Zhonghua Minguo Xiao Er Ke Yi Xue Hui Za Zhi Zhonghua Minguo Xiao Er Ke Yi Xue Hui 31(3): 151-157
1990
ISSN/ISBN: 0001-6578 PMID: 2275374 Document Number: 351909
From June 1988 to May 1989, 444 throat swab specimens were tested with an enzyme immunoassay kit for rapid diagnosis of group A streptococcal pharyngitis. The results were compared with those of throat culture method. The rapid test was positive in 37 of 42 culture-positive specimens and negative in 379 of 402 culture-negative specimens, thus yielding a total agreement of 93.7%, sensitivity 88.1%, specificity 94.7%, positive predictive value 61.7%, negative predictive value 98.7%. According to this practical application, we suggest that enzyme immunoassay test can be applied in outpatient clinics by busy pediatricians for rapid diagnosis of group A streptococcal pharyngitis.