Treatment of nephrotic syndrome with cyclosporin a
Furková, K.; Kaiserová, E.; Páleníková, O.; Hruskovic, I.; Slugen, I.; Arpasová, D.; Janota, S.; Nyulassy, S.
Ceskoslovenska Pediatrie 45(10): 591-595
1990
ISSN/ISBN: 0069-2328 PMID: 2092895 Document Number: 351404
The authors treated eight children with corticoid dependent syndrome caused by minor abnormalities of the glomeruli with Cyclosporin A. They administered Cyclosporin, 5 mg/kg/24 h., for a period of 8-16 weeks. In three patients they used Cyclosporin A alone, 5 children were given in addition 10 mg Prednisone per day. They achieved complete remission in all patients. During treatment they monitored haematological and biochemical parameters as well as Cyclosporin A levels; before treatment and after its termination they examined also immunological indicators. They did not observe any serious side effects of treatment.