Nephrotic syndrome after treatment with penicillamine in Wilson's disease
Hampel, R.; Meng, W.; Kallwellis, G.
Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 31(13): 507-511
1976
ISSN/ISBN: 0044-2542 PMID: 960872 Document Number: 108435
In a 33-year-old man with Wilson's disease a nephrotic syndrome appeared as a severe complication under penicillamine therapy. Under strong observation and exact controls of protein in the urine, leucocytes, differential blood picture and thrombocytes after interruption of the medication and retrogression of the side-effects a retarding new stabilisation of penicillamine can take place. Other side-effects of penicillamine observed as well as control measures under a long-term treatment with penicillamine are briefly discussed.